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KMID : 0367419690120110049
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Journal of Korean Pediatric Society
1969 Volume.12 No. 11 p.49 ~ p.57
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Cushing´s Syndrome in Infancy
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金炳吉/Kim, Pyung Kil
鄭瑾燮/尹德鎭/徐相賢/曺湘昊/Chung, Ki Sup/Yun, Duk Jin/Suh, Sang Hyon/Cho, Sang Ho
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Abstract
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There are little reports on the Cushing´s syndrome in children, especially in infancy in Korea We have found recently a case of Cushing´s syndrome in infancy arising from a female infant. She has been complained from eleven month of age with general obesity including buffalo hump, excessive weight gain, hirsutism and polyphgagia.
Laboratory tests revealed that- n(. thymic shadow_ in her chest X-ray, retarded bone age, hypertension,. increase3 urinary excretion of 17-tI.-ICS and 17-KS and eosinopenia but no evidence of osteoporosis in-her long bone swies. Two-days dexamethasone best were done and it was found that there were no-response to administration of dexamethasone in her urinary excretion of 17-OHCS.
IVP study showed that left kidney was displaced to downward than right side and an hen-egg size--radio-opaque shadow on the top of the left kidney.
The tumor was removed successfully by anterior transabdominal approach and that was found as a benign adenoma by microscopic study.
Hypertension, eosinopenia and hypokalemia were returned to normal level from 3 days after surgery but urinary 17-OHCS and 17-KS were returned to normal from two week after surgery.
The literature about Cushing´s syndrome in infancy were reviewed and compained with our case.
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KEYWORD
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